node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK53741.1 | EFK54242.1 | HMPREF0291_11398 | HMPREF0291_11899 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 0.921 |
EFK53741.1 | EFK54293.1 | HMPREF0291_11398 | HMPREF0291_11950 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.898 |
EFK53741.1 | amn | HMPREF0291_11398 | HMPREF0291_10516 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.907 |
EFK53741.1 | apt | HMPREF0291_11398 | HMPREF0291_11490 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.919 |
EFK53741.1 | cobB | HMPREF0291_11398 | HMPREF0291_10511 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000; Belongs to the sirtuin family. Class III subfamily. | 0.893 |
EFK53741.1 | hpt | HMPREF0291_11398 | HMPREF0291_10861 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
EFK53741.1 | rbsK | HMPREF0291_11398 | HMPREF0291_11111 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.857 |
EFK53741.1 | ribF | HMPREF0291_11398 | HMPREF0291_11397 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family. | 0.770 |
EFK53741.1 | rpsO | HMPREF0291_11398 | HMPREF0291_11399 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.664 |
EFK53741.1 | truB | HMPREF0291_11398 | HMPREF0291_11396 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.663 |
EFK54242.1 | EFK53741.1 | HMPREF0291_11899 | HMPREF0291_11398 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 0.921 |
EFK54242.1 | EFK54293.1 | HMPREF0291_11899 | HMPREF0291_11950 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.898 |
EFK54242.1 | amn | HMPREF0291_11899 | HMPREF0291_10516 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.908 |
EFK54242.1 | apt | HMPREF0291_11899 | HMPREF0291_11490 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.919 |
EFK54242.1 | cobB | HMPREF0291_11899 | HMPREF0291_10511 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000; Belongs to the sirtuin family. Class III subfamily. | 0.893 |
EFK54242.1 | hpt | HMPREF0291_11899 | HMPREF0291_10861 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
EFK54242.1 | rbsK | HMPREF0291_11899 | HMPREF0291_11111 | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.849 |
EFK54293.1 | EFK53741.1 | HMPREF0291_11950 | HMPREF0291_11398 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 0.898 |
EFK54293.1 | EFK54242.1 | HMPREF0291_11950 | HMPREF0291_11899 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910. | 0.898 |
EFK54293.1 | apt | HMPREF0291_11950 | HMPREF0291_11490 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.935 |