node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK54222.1 | EFK54223.1 | HMPREF0291_11879 | HMPREF0291_11880 | SWIM zinc finger domain protein; Pfam: PF04434. | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | 0.962 |
EFK54223.1 | EFK54222.1 | HMPREF0291_11880 | HMPREF0291_11879 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | SWIM zinc finger domain protein; Pfam: PF04434. | 0.962 |
EFK54223.1 | EFK54289.1 | HMPREF0291_11880 | HMPREF0291_11946 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | Hypothetical protein. | 0.930 |
EFK54223.1 | EFK54721.1 | HMPREF0291_11880 | HMPREF0291_11101 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | Ankyrin repeat protein; COG: COG0666; Pfam: PF00023; InterPro: IPR002110. | 0.870 |
EFK54223.1 | dnaN | HMPREF0291_11880 | HMPREF0291_10584 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.946 |
EFK54223.1 | polA | HMPREF0291_11880 | HMPREF0291_11722 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.972 |
EFK54223.1 | recA | HMPREF0291_11880 | HMPREF0291_11420 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.925 |
EFK54223.1 | rpoA | HMPREF0291_11880 | HMPREF0291_10223 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.987 |
EFK54223.1 | rpoB | HMPREF0291_11880 | HMPREF0291_10287 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.988 |
EFK54223.1 | rpoC | HMPREF0291_11880 | HMPREF0291_10286 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.964 |
EFK54223.1 | rpoZ | HMPREF0291_11880 | HMPREF0291_11535 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.989 |
EFK54289.1 | EFK54223.1 | HMPREF0291_11946 | HMPREF0291_11880 | Hypothetical protein. | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | 0.930 |
EFK54721.1 | EFK54223.1 | HMPREF0291_11101 | HMPREF0291_11880 | Ankyrin repeat protein; COG: COG0666; Pfam: PF00023; InterPro: IPR002110. | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | 0.870 |
EFK54721.1 | polA | HMPREF0291_11101 | HMPREF0291_11722 | Ankyrin repeat protein; COG: COG0666; Pfam: PF00023; InterPro: IPR002110. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.595 |
EFK54721.1 | recA | HMPREF0291_11101 | HMPREF0291_11420 | Ankyrin repeat protein; COG: COG0666; Pfam: PF00023; InterPro: IPR002110. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.521 |
dnaN | EFK54223.1 | HMPREF0291_10584 | HMPREF0291_11880 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | 0.946 |
dnaN | polA | HMPREF0291_10584 | HMPREF0291_11722 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
dnaN | recA | HMPREF0291_10584 | HMPREF0291_11420 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.921 |
dnaN | rpoA | HMPREF0291_10584 | HMPREF0291_10223 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.483 |
dnaN | rpoB | HMPREF0291_10584 | HMPREF0291_10287 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.448 |