| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG47341.1 | ybaK | HMPREF0183_1332 | HMPREF0183_1331 | Hypothetical protein; COG: COG3824; Pfam: PF06262; InterPro: IPR010428. | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.461 |
| EFG47907.1 | ybaK | HMPREF0183_0800 | HMPREF0183_1331 | Putative membrane protein; COG: COG5006; Pfam: PF00892; InterPro: IPR000620. | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.431 |
| aspS | lysS | HMPREF0183_1773 | HMPREF0183_0726 | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | 0.456 |
| aspS | proS | HMPREF0183_1773 | HMPREF0183_2033 | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.725 |
| aspS | ybaK | HMPREF0183_1773 | HMPREF0183_1331 | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.473 |
| lysS | aspS | HMPREF0183_0726 | HMPREF0183_1773 | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.456 |
| lysS | proS | HMPREF0183_0726 | HMPREF0183_2033 | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.841 |
| lysS | ybaK | HMPREF0183_0726 | HMPREF0183_1331 | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.407 |
| proS | aspS | HMPREF0183_2033 | HMPREF0183_1773 | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.725 |
| proS | lysS | HMPREF0183_2033 | HMPREF0183_0726 | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | 0.841 |
| proS | ybaK | HMPREF0183_2033 | HMPREF0183_1331 | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.447 |
| ybaK | EFG47341.1 | HMPREF0183_1331 | HMPREF0183_1332 | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Hypothetical protein; COG: COG3824; Pfam: PF06262; InterPro: IPR010428. | 0.461 |
| ybaK | EFG47907.1 | HMPREF0183_1331 | HMPREF0183_0800 | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Putative membrane protein; COG: COG5006; Pfam: PF00892; InterPro: IPR000620. | 0.431 |
| ybaK | aspS | HMPREF0183_1331 | HMPREF0183_1773 | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.473 |
| ybaK | lysS | HMPREF0183_1331 | HMPREF0183_0726 | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | lysine--tRNA ligase; COG: COG1190; Pfam: PF04329,PF04330,PF04331,PF01336,PF00152; InterPro: IPR002313. | 0.407 |
| ybaK | proS | HMPREF0183_1331 | HMPREF0183_2033 | YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR004369; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.447 |