STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
helYDEAD/DEAH box helicase; COG: COG4581; Pfam: PF00270,PF00271,PF08148; InterPro: IPR014001. (894 aa)    
Predicted Functional Partners:
tatA
Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
       0.767
tatC
Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
       0.767
EFG47075.1
Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG0545; Pfam: PF00254; InterPro: IPR001179.
 
     0.748
EFG47076.1
Hypothetical protein; COG: COG2378.
 
     0.705
EFG47070.1
Proteasome accessory factor PafA2; Pfam: PF03316,PF03136; InterPro: IPR004347.
 
     0.700
prcB
Proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
     0.688
prcA
Proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
     0.688
pafA
Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
     0.681
EFG47077.1
Hypothetical protein; COG: COG2378.
       0.651
typA
GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298.
      
 0.632
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.