STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG46899.1PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. (312 aa)    
Predicted Functional Partners:
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.986
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.911
EFG46901.1
CBS domain protein; COG: COG1253; Pfam: PF01595,PF00571,PF03471; InterPro: IPR000644.
  
    0.849
EFG46903.1
ATPase, AFG1 family; COG: COG1485; Pfam: PF03969; InterPro: IPR005654.
       0.705
ppk
Polyphosphate:nucleotide phosphotransferase, PPK2 family; COG: COG2326; Pfam: PF03976; InterPro: IPR005660.
       0.705
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
    0.703
EFG46898.1
RNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.691
dnaJ2
DnaJ domain protein; COG: COG0484; Pfam: PF01556; InterPro: IPR002939.
  
    0.639
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
     0.604
cmk
Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136.
  
    0.584
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.