STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
23.m06426Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (453 aa)    
Predicted Functional Partners:
19.m02257
Glycine cleavage T-protein (Aminomethyl transferase) domain containing protein.
  
 0.996
18.m06049
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.993
23.m05858
Dihydrolipoyl dehydrogenase.
  
 0.981
17.m10664
Adenylosuccinate lyase, putative.
  
  
 0.937
18.m06412
Adenylosuccinate synthetase; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
  
  
 0.931
17.m07167
LytB protein, putative.
  
 
 0.924
17.m07169
Pyridine nucleotide-disulphide oxidoreductase domain containing protein.
  
 
 0.901
17.m07248
1-deoxy-D-xylulose-5-phosphate synthase family protein.
  
 
 0.889
17.m07846
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.852
19.m02398
Uncharacterized protein.
    
 0.833
Your Current Organism:
Babesia bovis
NCBI taxonomy Id: 5865
Other names: B. bovis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.