STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
18.m06049Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (511 aa)    
Predicted Functional Partners:
23.m06239
Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative.
  
 0.995
17.m07574
Thymidylate kinase, putative.
  
 
 0.993
23.m06426
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.993
19.m02257
Glycine cleavage T-protein (Aminomethyl transferase) domain containing protein.
  
 
 0.992
19.m02176
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.984
18.m06523
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.956
BBOV_IV002070
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.956
18.m06569
Flavoprotein domain containing protein.
 
 
 0.953
17.m07147
Ham1 family protein.
  
 
 0.939
18.m06443
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.937
Your Current Organism:
Babesia bovis
NCBI taxonomy Id: 5865
Other names: B. bovis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.