STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BBBOND_0200380E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2068 aa)    
Predicted Functional Partners:
BBBOND_0305290
Ubiquitin-conjugating enzyme family protein, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.999
BBBOND_0403410
Ubiquitin transferase, HECT domain containing protein, putative.
   
 0.999
BBBOND_0205030
Ubiquitin-conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.999
BBBOND_0300510
E3 ubiquitin-protein ligase l.
   
 0.903
BBBOND_0108410
Ubiquitin-conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.898
BBBOND_0311890
Ribosomal protein S27a family protein, putative.
   
 0.842
BBBOND_0100770
HECT domain containing protein, putative.
   
 
 0.839
BBBOND_0300120
ThiF family domain containing protein, putative.
   
 0.827
BBBOND_0309460
ThiF family protein, putative.
   
 0.827
BBBOND_0105540
Uncharacterized protein.
   
 0.827
Your Current Organism:
Babesia bigemina
NCBI taxonomy Id: 5866
Other names: B. bigemina
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.