STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BBBOND_0309550REPLICATION FACTOR A 1, putative. (460 aa)    
Predicted Functional Partners:
BBBOND_0101830
3'-5' exonuclease domain containing protein, putative.
   
 0.999
BBBOND_0100790
Uncharacterized protein.
   
 0.968
BBBOND_0203740
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.954
BBBOND_0211250
Phosphatidylinositol 3-and 4-kinase family protein, putative; Belongs to the PI3/PI4-kinase family.
    
 0.942
BBBOND_0211550
DNA repair endonuclease, putative.
    
 0.941
BBBOND_0405665
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 0.934
BBBOND_0306140
DNA repair protein (Mre11) family protein, putative.
   
 0.917
BBBOND_0302830
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.916
BBBOND_0211660
Conserved hypothetcial protein, putative.
    
 0.867
BBBOND_0107580
DNA replication licensing factor MCM5, putative; Belongs to the MCM family.
   
 0.867
Your Current Organism:
Babesia bigemina
NCBI taxonomy Id: 5866
Other names: B. bigemina
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.