STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BBBOND_0303940Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (125 aa)    
Predicted Functional Partners:
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.976
BBBOND_0106310
Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.
   
 0.973
BBBOND_0205680
annotation not available
    
 0.908
BBBOND_0102750
DNA-directed RNA polymerase 2 subunit, putative.
    
 0.898
BBBOND_0308100
RNA polymerase Rpb4 family protein, putative.
   
 
 0.849
BBBOND_0206320
DNA-directed RNA polymerase II, putative.
    
 
 0.846
BBBOND_0102770
Transcription initiation factor TFIIB, putative.
    
 
 0.845
BBBOND_0111240
Uncharacterized protein.
    
 0.845
BBBOND_0311050
Probable DNA-directed RNA polymerase.
   
 
 0.834
BBBOND_0313690
RNA polymerase Rpb5, N-terminal domain containing protein, putative.
    
 
 0.829
Your Current Organism:
Babesia bigemina
NCBI taxonomy Id: 5866
Other names: B. bigemina
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.