ENSMMDP00005012016 protein (Myripristis murdjan)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

ENSMMDP00005012016

Tumor protein p53 binding protein, 2b. (1054 aa)

Predicted Functional Partners:

ENSMMDP00005053491

0.887

LOC115378176

0.786

tp53

0.776

ENSMMDP00005029784

0.746

rack1

0.726

ENSMMDP00005046895

0.724

ENSMMDP00005024580

0.709

ENSMMDP00005022069

0.706

LOC115379492

0.705

ENSMMDP00005004784

0.700

Your Current Organism:

Myripristis murdjan

NCBI taxonomy Id: 586833
Other names: M. murdjan, Ostichthys murdjan, Perca murdjan, Sciaena murdjan, pinecone soldierfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMDP00005004784	ENSMMDP00005012016	ENSMMDP00005004784	ENSMMDP00005012016	annotation not available	Tumor protein p53 binding protein, 2b.	0.700
ENSMMDP00005004784	ENSMMDP00005046895	ENSMMDP00005004784	ENSMMDP00005046895	annotation not available	annotation not available	0.694
ENSMMDP00005004784	ENSMMDP00005053491	ENSMMDP00005004784	ENSMMDP00005053491	annotation not available	annotation not available	0.452
ENSMMDP00005004784	LOC115379492	ENSMMDP00005004784	ENSMMDP00005029805	annotation not available	Uncharacterized LOC115379492.	0.846
ENSMMDP00005012016	ENSMMDP00005004784	ENSMMDP00005012016	ENSMMDP00005004784	Tumor protein p53 binding protein, 2b.	annotation not available	0.700
ENSMMDP00005012016	ENSMMDP00005022069	ENSMMDP00005012016	ENSMMDP00005022069	Tumor protein p53 binding protein, 2b.	annotation not available	0.706
ENSMMDP00005012016	ENSMMDP00005024580	ENSMMDP00005012016	ENSMMDP00005024580	Tumor protein p53 binding protein, 2b.	Interleukin 11a.	0.709
ENSMMDP00005012016	ENSMMDP00005029784	ENSMMDP00005012016	ENSMMDP00005029784	Tumor protein p53 binding protein, 2b.	annotation not available	0.746
ENSMMDP00005012016	ENSMMDP00005046895	ENSMMDP00005012016	ENSMMDP00005046895	Tumor protein p53 binding protein, 2b.	annotation not available	0.724
ENSMMDP00005012016	ENSMMDP00005053491	ENSMMDP00005012016	ENSMMDP00005053491	Tumor protein p53 binding protein, 2b.	annotation not available	0.887
ENSMMDP00005012016	LOC115378176	ENSMMDP00005012016	ENSMMDP00005051532	Tumor protein p53 binding protein, 2b.	Interferon a3-like.	0.786
ENSMMDP00005012016	LOC115379492	ENSMMDP00005012016	ENSMMDP00005029805	Tumor protein p53 binding protein, 2b.	Uncharacterized LOC115379492.	0.705
ENSMMDP00005012016	rack1	ENSMMDP00005012016	ENSMMDP00005041888	Tumor protein p53 binding protein, 2b.	Receptor for activated C kinase 1.	0.726
ENSMMDP00005012016	tp53	ENSMMDP00005012016	ENSMMDP00005051289	Tumor protein p53 binding protein, 2b.	Tumor protein p53.	0.776
ENSMMDP00005022069	ENSMMDP00005012016	ENSMMDP00005022069	ENSMMDP00005012016	annotation not available	Tumor protein p53 binding protein, 2b.	0.706
ENSMMDP00005022069	ENSMMDP00005029784	ENSMMDP00005022069	ENSMMDP00005029784	annotation not available	annotation not available	0.482
ENSMMDP00005022069	ENSMMDP00005046895	ENSMMDP00005022069	ENSMMDP00005046895	annotation not available	annotation not available	0.889
ENSMMDP00005022069	ENSMMDP00005053491	ENSMMDP00005022069	ENSMMDP00005053491	annotation not available	annotation not available	0.578
ENSMMDP00005022069	LOC115378176	ENSMMDP00005022069	ENSMMDP00005051532	annotation not available	Interferon a3-like.	0.406
ENSMMDP00005022069	LOC115379492	ENSMMDP00005022069	ENSMMDP00005029805	annotation not available	Uncharacterized LOC115379492.	0.759

page 1 of 3

Network Stats

number of nodes:

5

number of edges:

7

average node degree:

2.8

avg. local clustering coefficient:

0.8

expected number of edges:

7

PPI enrichment p-value:

0.476

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045454

Cell redox homeostasis

3 of 9

2.06

1.21

0.0048

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016667

Oxidoreductase activity, acting on a sulfur group of donors

4 of 20

1.84

1.7

0.00027

GO:0016668

Oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

3 of 9

2.06

1.47

0.0014

GO:0004148

Dihydrolipoyl dehydrogenase activity

2 of 2

2.54

1.15

0.0080

GO:0050660

Flavin adenine dinucleotide binding

3 of 37

1.45

0.76

0.0236

GO:0016491

Oxidoreductase activity

7 of 292

0.92

0.75

0.0014

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:701

Thioredoxin domain, and Cellular response to oxidative stress

5 of 11

2.2

3.25

2.41e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00380

Tryptophan metabolism

2 of 9

1.89

0.83

0.0254

map00310

Lysine degradation

2 of 9

1.89

0.83

0.0254

map00630

Glyoxylate and dicarboxylate metabolism

3 of 39

1.42

0.75

0.0239

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0676

Redox-active center

4 of 11

2.1

2.44

1.16e-05

KW-0274

FAD

3 of 25

1.62

1.11

0.0043

KW-0560

Oxidoreductase

6 of 166

1.1

1.01

0.00034

KW-0520

NAD

3 of 41

1.4

0.88

0.0103

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02852

Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

3 of 4

2.41

1.86

0.00033

PF00578

AhpC/TSA family

3 of 8

2.11

1.61

0.00078

PF13738

Pyridine nucleotide-disulphide oxidoreductase

2 of 3

2.36

1.02

0.0135

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036249

Thioredoxin-like superfamily

5 of 27

1.81

2.12

1.97e-05

IPR013766

Thioredoxin domain

4 of 13

2.03

2.07

6.44e-05

IPR012999

Pyridine nucleotide-disulphide oxidoreductase, class I, active site

3 of 3

2.54

2.03

0.00017

IPR001100

Pyridine nucleotide-disulphide oxidoreductase, class I

3 of 3

2.54

2.03

0.00017

IPR016156

FAD/NAD-linked reductase, dimerisation domain superfamily

3 of 4

2.41

2.0

0.00018

(more ...)

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