Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
mrcAPenicillin-binding protein 1A. (814 aa)    
Predicted Functional Partners:
spoVD
Stage V sporulation protein D; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.971
ftsI
Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
 
 0.966
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.946
dacB
D-alanyl-D-alanine carboxypeptidase DacB precursor.
  
  
 0.940
ponA1
Penicillin-binding protein 1A; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
0.938
dacA
D-alanyl-D-alanine carboxypeptidase DacA precursor; Belongs to the peptidase S11 family.
     
 0.924
dacC
D-alanyl-D-alanine carboxypeptidase DacC precursor; Belongs to the peptidase S11 family.
     
 0.924
pbpF
Penicillin-binding protein 1F.
  
  
0.924
lpoA
Penicillin-binding protein activator LpoA precursor.
  
 
 
 0.868
pilQ
Type IV pilus biogenesis and competence protein PilQ precursor; Belongs to the bacterial secretin family.
     
 0.721
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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