Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
emrK_1Putative multidrug resistance protein EmrK. (360 aa)    
Predicted Functional Partners:
emrB_1
Multidrug export protein EmrB.
 
 
 0.962
emrB_2
Multidrug export protein EmrB; Belongs to the major facilitator superfamily.
 
 
 0.839
emrB_3
Multidrug export protein EmrB; Belongs to the major facilitator superfamily.
 
 
 0.839
hsrA_2
Putative transport protein HsrA.
 
 
 0.814
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.765
cusC
Cation efflux system protein CusC precursor.
 
 
 0.754
ttgF
Toluene efflux pump outer membrane protein TtgF precursor.
 
 
 0.678
stp_1
Multidrug resistance protein stp.
 
 
 0.656
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.643
macB_2
Macrolide export ATP-binding/permease protein MacB.
  
  
 0.643
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.