Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sicA_2Chaperone protein SicA. (172 aa)    
Predicted Functional Partners:
APC09919.1
Type III secretion system protein SpaO.
 
  
 0.950
fliQ_2
Flagellar biosynthetic protein FliQ.
 
  
 0.946
prgK
Lipoprotein PrgK precursor.
 
  
 0.939
yscJ
Yop proteins translocation lipoprotein J precursor.
 
  
 0.922
APC09922.1
Flagellar biosynthesis protein FliR.
 
    0.912
sipB
Cell invasion protein SipB.
 
  
 0.904
mxiD
Outer membrane protein MxiD precursor.
 
  
 0.890
invA
Invasion protein InvA.
 
  
 0.879
spiA
Type III secretion system outer membrane protein SpiA precursor.
 
  
 0.816
ssaV
Secretion system apparatus protein SsaV.
 
  
 0.814
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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