Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cusBCation efflux system protein CusB precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (422 aa)    
Predicted Functional Partners:
cusA
Cation efflux system protein CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.999
cusC
Cation efflux system protein CusC precursor.
 
 
 0.981
cusF
Cation efflux system protein CusF precursor.
 
 
 0.965
cusS
Sensor kinase CusS; Member of a two-component regulatory system.
 
  
 0.879
cusR
Transcriptional regulatory protein CusR.
 
  
 0.848
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.846
macB_2
Macrolide export ATP-binding/permease protein MacB.
  
 
 0.846
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.809
APC10373.1
Hypothetical protein.
 
     0.702
bepE_2
Efflux pump membrane transporter BepE.
 
 
 0.574
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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