Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nhaRTranscriptional activator protein NhaR; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
nhaA
Na(+)/H(+) antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
  
 0.715
sdaA
L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family.
      
 0.585
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
      
 0.551
dusC_2
tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
      
 0.541
sdhC
Succinate dehydrogenase cytochrome b556 subunit.
      
 0.539
allS_2
HTH-type transcriptional activator AllS; Belongs to the LysR transcriptional regulatory family.
  
     0.527
dnaK_2
Chaperone protein DnaK.
  
     0.520
zapE
AFG1-like ATPase; Reduces the stability of FtsZ polymers in the presence of ATP.
      
 0.519
cyaA
Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.
      
 0.512
APC13960.1
Hypothetical protein.
  
     0.441
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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