STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcr_1Bicyclomycin resistance protein. (408 aa)    
Predicted Functional Partners:
davD
Glutarate-semialdehyde dehydrogenase DavD; Belongs to the aldehyde dehydrogenase family.
  
    0.781
tetA_1
Tetracycline resistance protein, class B.
  
   
 0.679
hpcD
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
       0.671
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
       0.671
stp_1
Multidrug resistance protein stp.
  
     0.565
hpcH
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family.
       0.491
tesE
2-hydroxyhexa-2,4-dienoate hydratase.
       0.488
csrA
Hypothetical protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
      
 0.470
csrA-2
Hypothetical protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
      
 0.441
tolC
Outer membrane protein TolC precursor.
      
 0.425
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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