| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alr_2 | glyA_2 | RB151_024240 | RB151_028150 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
| alr_2 | pssA | RB151_024240 | RB151_010310 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.901 |
| alr_2 | serB | RB151_024240 | RB151_006460 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Phosphoserine phosphatase. | 0.904 |
| alr_2 | trpA | RB151_024240 | RB151_023450 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| alr_2 | trpB | RB151_024240 | RB151_023440 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cdh | cdsA_1 | RB151_041500 | RB151_035420 | CDP-diacylglycerol pyrophosphatase. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.907 |
| cdh | pgsA | RB151_041500 | RB151_018310 | CDP-diacylglycerol pyrophosphatase. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.909 |
| cdh | pssA | RB151_041500 | RB151_010310 | CDP-diacylglycerol pyrophosphatase. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.906 |
| cdsA_1 | cdh | RB151_035420 | RB151_041500 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | CDP-diacylglycerol pyrophosphatase. | 0.907 |
| cdsA_1 | pgsA | RB151_035420 | RB151_018310 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.957 |
| cdsA_1 | psd | RB151_035420 | RB151_041730 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.595 |
| cdsA_1 | pssA | RB151_035420 | RB151_010310 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.943 |
| glyA_2 | alr_2 | RB151_028150 | RB151_024240 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.912 |
| glyA_2 | pssA | RB151_028150 | RB151_010310 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.922 |
| glyA_2 | serB | RB151_028150 | RB151_006460 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.933 |
| glyA_2 | trpA | RB151_028150 | RB151_023450 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.918 |
| glyA_2 | trpB | RB151_028150 | RB151_023440 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
| pgsA | cdh | RB151_018310 | RB151_041500 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diacylglycerol pyrophosphatase. | 0.909 |
| pgsA | cdsA_1 | RB151_018310 | RB151_035420 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.957 |
| pgsA | psd | RB151_018310 | RB151_041730 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.654 |