acrZ protein (Providencia rettgeri) - STRING interaction network

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acrZ

Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (50 aa)

Predicted Functional Partners:

tolC

0.740

modE

0.628

bepE_1

0.421

acrB_1

0.421

acrB_2

0.421

bepE_2

0.421

Your Current Organism:

Providencia rettgeri

NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acrB_1	acrZ	RB151_004840	RB151_011500	Multidrug efflux pump subunit AcrB.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.421
acrB_1	bepE_1	RB151_004840	RB151_004830	Multidrug efflux pump subunit AcrB.	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.992
acrB_1	tolC	RB151_004840	RB151_036110	Multidrug efflux pump subunit AcrB.	Outer membrane protein TolC precursor.	0.452
acrB_2	acrZ	RB151_033900	RB151_011500	Multidrug efflux pump subunit AcrB.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.421
acrB_2	tolC	RB151_033900	RB151_036110	Multidrug efflux pump subunit AcrB.	Outer membrane protein TolC precursor.	0.961
acrZ	acrB_1	RB151_011500	RB151_004840	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Multidrug efflux pump subunit AcrB.	0.421
acrZ	acrB_2	RB151_011500	RB151_033900	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Multidrug efflux pump subunit AcrB.	0.421
acrZ	bepE_1	RB151_011500	RB151_004830	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.421
acrZ	bepE_2	RB151_011500	RB151_040620	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Efflux pump membrane transporter BepE.	0.421
acrZ	modE	RB151_011500	RB151_011490	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Transcriptional regulator ModE.	0.628
acrZ	tolC	RB151_011500	RB151_036110	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	Outer membrane protein TolC precursor.	0.740
bepE_1	acrB_1	RB151_004830	RB151_004840	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	Multidrug efflux pump subunit AcrB.	0.992
bepE_1	acrZ	RB151_004830	RB151_011500	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.421
bepE_1	tolC	RB151_004830	RB151_036110	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	Outer membrane protein TolC precursor.	0.464
bepE_2	acrZ	RB151_040620	RB151_011500	Efflux pump membrane transporter BepE.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.421
modE	acrZ	RB151_011490	RB151_011500	Transcriptional regulator ModE.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.628
tolC	acrB_1	RB151_036110	RB151_004840	Outer membrane protein TolC precursor.	Multidrug efflux pump subunit AcrB.	0.452
tolC	acrB_2	RB151_036110	RB151_033900	Outer membrane protein TolC precursor.	Multidrug efflux pump subunit AcrB.	0.961
tolC	acrZ	RB151_036110	RB151_011500	Outer membrane protein TolC precursor.	Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.	0.740
tolC	bepE_1	RB151_036110	RB151_004830	Outer membrane protein TolC precursor.	Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.464

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