Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
emrK_2Putative multidrug resistance protein EmrK. (331 aa)    
Predicted Functional Partners:
ybhF_1
Putative ABC transporter ATP-binding protein YbhF.
 
  
 0.977
ybhR
Inner membrane transport permease YbhR.
 
  
 0.967
ybhS_1
Inner membrane transport permease YbhS.
 
  
 0.967
acnR
HTH-type transcriptional repressor AcnR.
 
  
 0.735
yhhJ
Inner membrane transport permease YhhJ.
 
  
 0.710
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.702
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.691
cusC
Cation efflux system protein CusC precursor.
 
 
 0.613
tolC
Outer membrane protein TolC precursor.
  
 
 0.568
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.567
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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