Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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macB_1Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (647 aa)    
Predicted Functional Partners:
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
0.996
macA_1
Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.995
macA_2
Macrolide export protein MacA.
 
 
 0.963
acrA
Multidrug efflux pump subunit AcrA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.882
mdtE
Multidrug resistance protein MdtE precursor.
 
 
 0.867
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.847
mdtA_1
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.846
cusB
Cation efflux system protein CusB precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.846
mdtA_2
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.846
tolC
Outer membrane protein TolC precursor.
  
 
 0.814
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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