STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
allS_2HTH-type transcriptional activator AllS; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
hcaR_1
Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family.
  
     0.705
cynR_2
HTH-type transcriptional regulator CynR; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.705
benM_2
HTH-type transcriptional regulator BenM.
  
     0.702
topB_2
DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   
 0.683
cynR_1
HTH-type transcriptional regulator CynR; Belongs to the LysR transcriptional regulatory family.
  
     0.673
ydhC_2
Inner membrane transport protein YdhC.
 
     0.646
tamB
Translocation and assembly module TamB.
      
 0.637
tfdS
HTH-type transcriptional regulator TfdS; Belongs to the LysR transcriptional regulatory family.
  
     0.569
gltC_2
HTH-type transcriptional regulator GltC; Belongs to the LysR transcriptional regulatory family.
  
     0.567
yjiE_2
HTH-type transcriptional regulator YjiE.
  
     0.537
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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