| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APC11018.1 | gloA | RB151_013330 | RB151_019630 | Putative metallo-hydrolase. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.939 |
| APC11018.1 | gloB | RB151_013330 | RB151_007750 | Putative metallo-hydrolase. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.907 |
| dsdA | ghrA | RB151_039390 | RB151_020680 | D-serine dehydratase. | Glyoxylate/hydroxypyruvate reductase A. | 0.800 |
| dsdA | ghrB | RB151_039390 | RB151_039350 | D-serine dehydratase. | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.800 |
| dsdA | gloA | RB151_039390 | RB151_019630 | D-serine dehydratase. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.800 |
| dsdA | ilvA | RB151_039390 | RB151_042280 | D-serine dehydratase. | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.914 |
| dsdA | sdaA | RB151_039390 | RB151_024160 | D-serine dehydratase. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
| dsdA | sdaB | RB151_039390 | RB151_012530 | D-serine dehydratase. | L-serine dehydratase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.925 |
| ghrA | dsdA | RB151_020680 | RB151_039390 | Glyoxylate/hydroxypyruvate reductase A. | D-serine dehydratase. | 0.800 |
| ghrA | ghrB | RB151_020680 | RB151_039350 | Glyoxylate/hydroxypyruvate reductase A. | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.922 |
| ghrA | gloA | RB151_020680 | RB151_019630 | Glyoxylate/hydroxypyruvate reductase A. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.900 |
| ghrA | ilvA | RB151_020680 | RB151_042280 | Glyoxylate/hydroxypyruvate reductase A. | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.822 |
| ghrA | sdaA | RB151_020680 | RB151_024160 | Glyoxylate/hydroxypyruvate reductase A. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.800 |
| ghrA | sdaB | RB151_020680 | RB151_012530 | Glyoxylate/hydroxypyruvate reductase A. | L-serine dehydratase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.800 |
| ghrA | trpA | RB151_020680 | RB151_023450 | Glyoxylate/hydroxypyruvate reductase A. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.847 |
| ghrA | trpB | RB151_020680 | RB151_023440 | Glyoxylate/hydroxypyruvate reductase A. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.841 |
| ghrB | dsdA | RB151_039350 | RB151_039390 | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | D-serine dehydratase. | 0.800 |
| ghrB | ghrA | RB151_039350 | RB151_020680 | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glyoxylate/hydroxypyruvate reductase A. | 0.922 |
| ghrB | gloA | RB151_039350 | RB151_019630 | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.909 |
| ghrB | ilvA | RB151_039350 | RB151_042280 | Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.810 |
