Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
emrK_3Putative multidrug resistance protein EmrK. (356 aa)    
Predicted Functional Partners:
ybhF_2
Putative ABC transporter ATP-binding protein YbhF.
 
  
 0.983
yhhJ
Inner membrane transport permease YhhJ.
 
  
 0.973
ybhS_1
Inner membrane transport permease YbhS.
 
  
 0.771
ybhF_1
Putative ABC transporter ATP-binding protein YbhF.
 
  
 0.764
ybhR
Inner membrane transport permease YbhR.
 
  
 0.724
ybhS_2
Inner membrane transport permease YbhS.
 
  
 0.720
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.709
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.704
cusC
Cation efflux system protein CusC precursor.
 
 
 0.605
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.568
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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