Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arpCAntibiotic efflux pump outer membrane protein ArpC precursor. (436 aa)    
Predicted Functional Partners:
acrA
Multidrug efflux pump subunit AcrA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.950
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
 
 0.948
acrB_2
Multidrug efflux pump subunit AcrB.
 
 0.931
tolC
Outer membrane protein TolC precursor.
     
 0.919
ttgF
Toluene efflux pump outer membrane protein TtgF precursor.
     
  0.900
macA_2
Macrolide export protein MacA.
 
 
 0.874
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.847
aaeA
P-hydroxybenzoic acid efflux pump subunit AaeA.
 
 
 0.835
cusB
Cation efflux system protein CusB precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.809
emrA_1
Multidrug export protein EmrA.
 
 
 0.768
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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