STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabF_13-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (412 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase.
 0.995
fabG_2
3-oxoacyl-[acyl-carrier-protein] reductase FabG.
 
 0.994
fabH_2
3-oxoacyl-[acyl-carrier-protein] synthase 3.
 
 
 0.989
fabH_1
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.988
fabG_4
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.974
fabG_6
3-oxoacyl-[acyl-carrier-protein] reductase FabG.
 
 0.963
APC09964.1
3-oxoacyl-(acyl carrier protein) synthase III.
  
 
 0.959
fabG_1
3-oxoacyl-[acyl-carrier-protein] reductase FabG.
 
 0.944
fabV
Putative reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.
  
 
 0.934
bdcA
Cyclic-di-GMP-binding biofilm dispersal mediator protein.
 
 0.930
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.