Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdtA_2Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (416 aa)    
Predicted Functional Partners:
mdtB
Multidrug resistance protein MdtB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
 0.983
mdtC
Multidrug resistance protein MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 
 0.983
bepE_2
Efflux pump membrane transporter BepE.
 
 
 0.865
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.846
macB_2
Macrolide export ATP-binding/permease protein MacB.
  
 
 0.846
acrB_2
Multidrug efflux pump subunit AcrB.
 
 
 0.845
bepE_1
Efflux pump membrane transporter BepE; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.840
baeR
Transcriptional regulatory protein BaeR.
  
  
 0.833
acrB_1
Multidrug efflux pump subunit AcrB.
 
 
 0.828
tolC
Outer membrane protein TolC precursor.
  
 0.828
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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