| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dapD | lysC | RB151_035510 | RB151_004420 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.833 |
| dapD | thiC | RB151_035510 | RB151_004060 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.837 |
| dapD | thiD | RB151_035510 | RB151_024820 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.749 |
| lysC | dapD | RB151_004420 | RB151_035510 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.833 |
| lysC | thiC | RB151_004420 | RB151_004060 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.743 |
| lysC | thiD | RB151_004420 | RB151_024820 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.753 |
| moeB_1 | thiC | RB151_011930 | RB151_004060 | Molybdopterin-synthase adenylyltransferase. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.755 |
| moeB_1 | thiD | RB151_011930 | RB151_024820 | Molybdopterin-synthase adenylyltransferase. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.728 |
| moeB_1 | thiE | RB151_011930 | RB151_004050 | Molybdopterin-synthase adenylyltransferase. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.772 |
| moeB_1 | thiG | RB151_011930 | RB151_004020 | Molybdopterin-synthase adenylyltransferase. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.851 |
| moeB_1 | thiS | RB151_011930 | RB151_004030 | Molybdopterin-synthase adenylyltransferase. | Sulfur carrier protein ThiS. | 0.785 |
| ribD | thiC | RB151_007180 | RB151_004060 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.566 |
| ribD | thiD | RB151_007180 | RB151_024820 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.626 |
| ribD | thiE | RB151_007180 | RB151_004050 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.577 |
| ribD | thiG | RB151_007180 | RB151_004020 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.541 |
| thiC | dapD | RB151_004060 | RB151_035510 | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.837 |
| thiC | lysC | RB151_004060 | RB151_004420 | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.743 |
| thiC | moeB_1 | RB151_004060 | RB151_011930 | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Molybdopterin-synthase adenylyltransferase. | 0.755 |
| thiC | ribD | RB151_004060 | RB151_007180 | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.566 |
| thiC | thiD | RB151_004060 | RB151_024820 | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.997 |