| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APC10459.1 | ampD | RB151_007530 | RB151_030280 | Muropeptide transporter. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD. | 0.466 |
| APC10459.1 | anmK | RB151_007530 | RB151_019670 | Muropeptide transporter. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.631 |
| APC10459.1 | nagZ | RB151_007530 | RB151_025450 | Muropeptide transporter. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.532 |
| APC10459.1 | ybbD | RB151_007530 | RB151_043430 | Muropeptide transporter. | Putative lipoprotein YbbD precursor. | 0.441 |
| APC12219.1 | APC12220.1 | RB151_025480 | RB151_025490 | Hypothetical protein. | HIT-like protein. | 0.947 |
| APC12219.1 | lpoB | RB151_025480 | RB151_025470 | Hypothetical protein. | Penicillin-binding protein activator LpoB precursor; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. | 0.947 |
| APC12219.1 | nagZ | RB151_025480 | RB151_025450 | Hypothetical protein. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.646 |
| APC12219.1 | thiK | RB151_025480 | RB151_025460 | Hypothetical protein. | Thiamine kinase. | 0.884 |
| APC12220.1 | APC12219.1 | RB151_025490 | RB151_025480 | HIT-like protein. | Hypothetical protein. | 0.947 |
| APC12220.1 | lpoB | RB151_025490 | RB151_025470 | HIT-like protein. | Penicillin-binding protein activator LpoB precursor; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. | 0.868 |
| APC12220.1 | nagZ | RB151_025490 | RB151_025450 | HIT-like protein. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.608 |
| APC12220.1 | thiK | RB151_025490 | RB151_025460 | HIT-like protein. | Thiamine kinase. | 0.830 |
| amiD | nagZ | RB151_004370 | RB151_025450 | N-acetylmuramoyl-L-alanine amidase AmiD precursor. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.584 |
| ampD | APC10459.1 | RB151_030280 | RB151_007530 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD. | Muropeptide transporter. | 0.466 |
| ampD | anmK | RB151_030280 | RB151_019670 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.495 |
| ampD | nagZ | RB151_030280 | RB151_025450 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.724 |
| anmK | APC10459.1 | RB151_019670 | RB151_007530 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Muropeptide transporter. | 0.631 |
| anmK | ampD | RB151_019670 | RB151_030280 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD. | 0.495 |
| anmK | nagZ | RB151_019670 | RB151_025450 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.781 |
| anmK | ybbD | RB151_019670 | RB151_043430 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative lipoprotein YbbD precursor. | 0.565 |