| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crl | cyaA | RB151_009890 | RB151_041970 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.716 |
| crl | lpp | RB151_009890 | RB151_019480 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Major outer membrane lipoprotein Lpp precursor. | 0.724 |
| crl | lptC | RB151_009890 | RB151_037500 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.425 |
| crl | ompD | RB151_009890 | RB151_013370 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Outer membrane porin protein OmpD precursor; Belongs to the Gram-negative porin family. | 0.508 |
| crl | viaA | RB151_009890 | RB151_000380 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Hypothetical protein. | 0.766 |
| crl | yciS | RB151_009890 | RB151_023190 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Inner membrane protein YciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.718 |
| crl | yeeX | RB151_009890 | RB151_025740 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Hypothetical protein; Belongs to the UPF0265 family. | 0.662 |
| crl | zapB | RB151_009890 | RB151_043320 | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.742 |
| cyaA | crl | RB151_041970 | RB151_009890 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.716 |
| cyaA | lpp | RB151_041970 | RB151_019480 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Major outer membrane lipoprotein Lpp precursor. | 0.664 |
| cyaA | lptC | RB151_041970 | RB151_037500 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.596 |
| cyaA | mukE | RB151_041970 | RB151_013280 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Chromosome partition protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.673 |
| cyaA | mukF | RB151_041970 | RB151_013270 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Chromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.656 |
| cyaA | ompD | RB151_041970 | RB151_013370 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Outer membrane porin protein OmpD precursor; Belongs to the Gram-negative porin family. | 0.504 |
| cyaA | viaA | RB151_041970 | RB151_000380 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Hypothetical protein. | 0.638 |
| cyaA | yciS | RB151_041970 | RB151_023190 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Inner membrane protein YciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.768 |
| cyaA | yeeX | RB151_041970 | RB151_025740 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Hypothetical protein; Belongs to the UPF0265 family. | 0.710 |
| cyaA | zapB | RB151_041970 | RB151_043320 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.668 |
| lpp | crl | RB151_019480 | RB151_009890 | Major outer membrane lipoprotein Lpp precursor. | Sigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.724 |
| lpp | cyaA | RB151_019480 | RB151_041970 | Major outer membrane lipoprotein Lpp precursor. | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.664 |