| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APC11637.1 | ascD_2 | RB151_019640 | RB151_026450 | Hypothetical protein. | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | 0.698 |
| APC11637.1 | nrdA | RB151_019640 | RB151_026430 | Hypothetical protein. | Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.660 |
| APC11637.1 | nrdB | RB151_019640 | RB151_026440 | Hypothetical protein. | Ribonucleoside-diphosphate reductase 1 subunit beta. | 0.679 |
| ascD_2 | APC11637.1 | RB151_026450 | RB151_019640 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Hypothetical protein. | 0.698 |
| ascD_2 | dcd | RB151_026450 | RB151_012310 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.499 |
| ascD_2 | iscS | RB151_026450 | RB151_028020 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.529 |
| ascD_2 | iscU | RB151_026450 | RB151_028010 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.603 |
| ascD_2 | nfuA | RB151_026450 | RB151_002630 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.709 |
| ascD_2 | nrdA | RB151_026450 | RB151_026430 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.959 |
| ascD_2 | nrdB | RB151_026450 | RB151_026440 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Ribonucleoside-diphosphate reductase 1 subunit beta. | 0.963 |
| ascD_2 | nuoC | RB151_026450 | RB151_026700 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.901 |
| ascD_2 | ubiG | RB151_026450 | RB151_026420 | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.431 |
| dcd | ascD_2 | RB151_012310 | RB151_026450 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | 0.499 |
| dcd | nrdA | RB151_012310 | RB151_026430 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.639 |
| dcd | nrdB | RB151_012310 | RB151_026440 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside-diphosphate reductase 1 subunit beta. | 0.604 |
| iscS | ascD_2 | RB151_028020 | RB151_026450 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | 0.529 |
| iscS | iscU | RB151_028020 | RB151_028010 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.999 |
| iscS | nfuA | RB151_028020 | RB151_002630 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.963 |
| iscS | nuoC | RB151_028020 | RB151_026700 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.754 |
| iscU | ascD_2 | RB151_028010 | RB151_026450 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase. | 0.603 |