STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hmpFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (399 aa)    
Predicted Functional Partners:
ytfE
Iron-sulfur cluster repair protein YtfE; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
  
  
 0.963
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.776
nsrR
HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.
 
   
 0.730
tehB
Putative S-adenosyl-L-methionine-dependent methyltransferase TehB.
  
  
 0.722
fnr_1
Fumarate and nitrate reduction regulatory protein.
  
  
 0.655
fnr_2
Fumarate and nitrate reduction regulatory protein.
  
  
 0.655
crp_2
cAMP receptor protein.
  
  
 0.602
norV
Anaerobic nitric oxide reductase flavorubredoxin.
  
  
 0.596
APC12662.1
Low-density lipoprotein receptor repeat class B.
  
     0.581
narG
Respiratory nitrate reductase 1 alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.555
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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