Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemR_2Hemin receptor precursor. (666 aa)    
Predicted Functional Partners:
hmuT
Hemin-binding periplasmic protein HmuT precursor.
 
  
 0.893
hemS_3
Hemin transport protein HemS.
 
   
 0.890
hmuV
Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
   
 0.830
hmuU_2
Hemin transport system permease protein HmuU; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.804
hemS_1
Hemin transport protein HemS.
 
   
 0.647
hemS_2
Hemin transport protein HemS.
 
   
 0.593
APC12623.1
Hypothetical protein.
       0.550
APC12622.1
Hypothetical protein.
  
  
 0.539
APC10350.1
Transport protein TonB.
 
 
 0.528
APC12026.1
Transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.497
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.