Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrfDPolysulfide reductase, NrfD. (318 aa)    
Predicted Functional Partners:
nrfB
Cytochrome c-type protein NrfB precursor.
 
  
 0.987
nrfA
Cytochrome c-552 precursor; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
 
  
 0.961
ydhX
Putative ferredoxin-like protein YdhX precursor.
 
  
 0.945
ccmF_2
Cytochrome c-type biogenesis protein CcmF.
 
  
 0.867
nrfG
Formate-dependent nitrite reductase complex subunit NrfG; Possible subunit of a heme lyase.
 
  
 0.861
napD
Assembly protein for periplasmic nitrate reductase; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
  
   
 0.788
ttrS
Tetrathionate sensor histidine kinase TtrS.
 
   
 0.759
yccM_1
Putative electron transport protein YccM.
  
  
 0.737
APC12783.1
Quinol dehydrogenase periplasmic component.
 
  
 0.708
ttrB
Tetrathionate reductase subunit B precursor.
 
  
 0.641
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (12%) [HD]