Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
marRMultiple antibiotic resistance protein MarR. (178 aa)    
Predicted Functional Partners:
soxR
Redox-sensitive transcriptional activator SoxR.
  
   
 0.518
soxS
Regulatory protein SoxS.
   
  
 0.463
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
  
    0.446
parC
DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.444
ftsI
Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
   
  
 0.440
glnS
Glutamine--tRNA ligase.
   
    0.439
acrA
Multidrug efflux pump subunit AcrA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.439
acrR
HTH-type transcriptional regulator AcrR.
      
 0.438
emrB_2
Multidrug export protein EmrB; Belongs to the major facilitator superfamily.
     
 0.436
emrB_3
Multidrug export protein EmrB; Belongs to the major facilitator superfamily.
     
 0.436
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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