Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cueR_2HTH-type transcriptional regulator CueR. (136 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.755
adhR
HTH-type transcriptional regulator AdhR.
  
 
   0.741
copA
Copper-exporting P-type ATPase A.
 
  
 0.713
cueO
Blue copper oxidase CueO precursor.
 
  
 0.707
cusR
Transcriptional regulatory protein CusR.
    
 
 0.686
yfgC
TPR repeat-containing protein YfgC precursor; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
      
 0.649
nudE
ADP compounds hydrolase NudE.
   
    0.581
cusS
Sensor kinase CusS; Member of a two-component regulatory system.
      
 0.581
cusA
Cation efflux system protein CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.530
cusF
Cation efflux system protein CusF precursor.
   
  
 0.517
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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