Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acrB_2Multidrug efflux pump subunit AcrB. (1052 aa)    
Predicted Functional Partners:
acrA
Multidrug efflux pump subunit AcrA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 0.998
tolC
Outer membrane protein TolC precursor.
  
 0.961
cusC
Cation efflux system protein CusC precursor.
 
 0.940
ttgF
Toluene efflux pump outer membrane protein TtgF precursor.
 
 0.934
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 0.931
mdtE
Multidrug resistance protein MdtE precursor.
 
 
 0.868
mdtA_2
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.845
macA_2
Macrolide export protein MacA.
 
 
 0.754
macA_1
Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.718
acrR
HTH-type transcriptional regulator AcrR.
     
 0.698
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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