Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
btuF_2Vitamin B12-binding protein precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (279 aa)    
Predicted Functional Partners:
btuC
Vitamin B12 import system permease protein BtuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
 
 
 0.966
btuD
Vitamin B12 import ATP-binding protein BtuD.
  
 
 0.905
hmuU_2
Hemin transport system permease protein HmuU; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.838
APC13293.1
Putative ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.828
APC10173.1
Putative ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.823
APC13294.1
Putative ABC transporter permease protein.
 
 
 0.817
hmuU_1
Hemin transport system permease protein HmuU; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.751
hmuV
Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
   
 0.747
mtnN
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...]
  
  
 0.746
APC10172.1
Putative ABC transporter ATP-binding protein.
 
 
 0.670
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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