STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvA_2Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (313 aa)    
Predicted Functional Partners:
APC13216.1
Hypothetical protein.
  
    0.771
rlmM
Ribosomal RNA large subunit methyltransferase M; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.717
cynR_2
HTH-type transcriptional regulator CynR; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.700
benM_2
HTH-type transcriptional regulator BenM.
  
     0.679
cmpR
HTH-type transcriptional activator CmpR.
  
     0.663
fadR
Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism.
  
  
 0.656
gltR_3
HTH-type transcriptional regulator GltR; Belongs to the LysR transcriptional regulatory family.
  
     0.622
yejL
Hypothetical protein; Belongs to the UPF0352 family.
  
     0.599
tfdS
HTH-type transcriptional regulator TfdS; Belongs to the LysR transcriptional regulatory family.
  
     0.595
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.579
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.