Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thiBThiamine-binding periplasmic protein precursor. (334 aa)    
Predicted Functional Partners:
cysW_2
Sulfate transport system permease protein CysW.
 
 
 0.996
thiQ_2
Thiamine import ATP-binding protein ThiQ; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
 
 
  0.980
polB
DNA polymerase II.
       0.601
cysT_2
Sulfate transport system permease protein CysT.
 
  
 0.522
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
   
  
 0.469
ptsI_2
Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
       0.447
rppH_2
RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
       0.447
APC13205.1
Hypothetical protein; Belongs to the UPF0325 family.
  
     0.410
fbp
Fructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family.
     
 0.405
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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