STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hybCHydrogenase-2 large chain precursor; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)    
Predicted Functional Partners:
hybO
Hydrogenase-2 small chain precursor.
 
 0.999
hypA
Hydrogenase nickel incorporation protein HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.991
hybD
Hydrogenase 2 maturation protease.
 
 
 0.978
hybB
Putative Ni/Fe-hydrogenase 2 b-type cytochrome subunit.
 
  
 0.968
hybE
Hydrogenase-2 operon protein HybE.
 
  
 0.966
fdnH_2
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit.
 
  
 0.951
hypD
Hydrogenase isoenzymes formation protein HypD; Belongs to the HypD family.
 
 
 0.946
hypE
Hydrogenase isoenzymes formation protein HypE.
 
   
 0.925
hypC
Hydrogenase isoenzymes formation protein HypC.
 
 
 0.925
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
 
   
 0.904
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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