close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mlaEPutative phospholipid ABC transporter permease protein MlaE. (260 aa)    
Predicted Functional Partners:
mlaD
Putative phospholipid ABC transporter-binding protein MlaD.
 
 0.999
mlaF
Putative phospholipid import ATP-binding protein MlaF.
 
 0.999
mlaC
Putative phospholipid-binding protein MlaC precursor.
 
 
 0.975
mlaB
Putative phospholipid ABC transporter-binding protein MlaB.
  
 0.960
lptB_1
Lipopolysaccharide export system ATP-binding protein LptB.
 
  
  0.569
mlaA
Putative phospholipid-binding lipoprotein MlaA precursor.
 
   
 0.555
lptF
Lipopolysaccharide export system permease protein LptF.
  
  
 0.547
lptG
Lipopolysaccharide export system permease protein LptG.
  
  
 0.540
surE_1
5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
 
     0.489
proX_1
Glycine betaine-binding periplasmic protein precursor.
     
 0.473
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.