STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bepE_2Efflux pump membrane transporter BepE. (1046 aa)    
Predicted Functional Partners:
mdtE
Multidrug resistance protein MdtE precursor.
 
 0.965
acrA
Multidrug efflux pump subunit AcrA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.858
mdtA_2
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.837
cusC
Cation efflux system protein CusC precursor.
 
 0.775
mdtA_1
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.747
macA_2
Macrolide export protein MacA.
 
 
 0.659
macA_1
Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.620
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 0.616
cusB
Cation efflux system protein CusB precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.509
acrZ
Multidrug efflux pump accessory protein AcrZ; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
    
   0.491
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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