APC13728.1 protein (Providencia rettgeri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

APC13728.1

Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (155 aa)

Predicted Functional Partners:

nrdD

0.997

queF

0.871

queD

0.822

queC

0.717

APC12155.1

0.680

guaA

0.545

pyrB

0.439

folE

0.438

pyrI

0.416

Your Current Organism:

Providencia rettgeri

NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC12155.1	APC13728.1	RB151_024840	RB151_040820	Hypothetical protein.	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	0.680
APC13728.1	APC12155.1	RB151_040820	RB151_024840	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	Hypothetical protein.	0.680
APC13728.1	folE	RB151_040820	RB151_011960	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	GTP cyclohydrolase 1.	0.438
APC13728.1	guaA	RB151_040820	RB151_024330	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.545
APC13728.1	nrdD	RB151_040820	RB151_040810	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	Anaerobic ribonucleoside-triphosphate reductase.	0.997
APC13728.1	pyrB	RB151_040820	RB151_040780	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.439
APC13728.1	pyrI	RB151_040820	RB151_040790	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.	0.416
APC13728.1	queC	RB151_040820	RB151_007640	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.717
APC13728.1	queD	RB151_040820	RB151_035010	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	6-carboxy-5,6,7,8-tetrahydropterin synthase.	0.822
APC13728.1	queF	RB151_040820	RB151_035590	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.871
folE	APC13728.1	RB151_011960	RB151_040820	GTP cyclohydrolase 1.	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	0.438
folE	guaA	RB151_011960	RB151_024330	GTP cyclohydrolase 1.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.597
folE	nrdD	RB151_011960	RB151_040810	GTP cyclohydrolase 1.	Anaerobic ribonucleoside-triphosphate reductase.	0.800
folE	queC	RB151_011960	RB151_007640	GTP cyclohydrolase 1.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.595
folE	queD	RB151_011960	RB151_035010	GTP cyclohydrolase 1.	6-carboxy-5,6,7,8-tetrahydropterin synthase.	0.977
folE	queF	RB151_011960	RB151_035590	GTP cyclohydrolase 1.	NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.626
guaA	APC13728.1	RB151_024330	RB151_040820	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	0.545
guaA	folE	RB151_024330	RB151_011960	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	GTP cyclohydrolase 1.	0.597
guaA	pyrB	RB151_024330	RB151_040780	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.795
guaA	queC	RB151_024330	RB151_007640	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.567

page 1 of 3

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About