Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdtN_2Multidrug resistance protein MdtN. (323 aa)    
Predicted Functional Partners:
ybhS_2
Inner membrane transport permease YbhS.
 
  
 0.952
ybhS_2-2
ABC-2 family transporter protein.
 
    0.946
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.685
macB_1
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.643
ybhF_1
Putative ABC transporter ATP-binding protein YbhF.
 
  
 0.582
tolC
Outer membrane protein TolC precursor.
 
 
 0.560
mdtE
Multidrug resistance protein MdtE precursor.
 
     0.548
arpC
Antibiotic efflux pump outer membrane protein ArpC precursor.
 
 
 0.545
yhhJ
Inner membrane transport permease YhhJ.
 
  
 0.523
acrB_2
Multidrug efflux pump subunit AcrB.
 
   
 0.511
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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