Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fbpFructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family. (283 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.960
tktA_1
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.946
tktA_2
Transketolase 1; Belongs to the transketolase family.
  
 
 0.946
fbaA
Fructose-bisphosphate aldolase class 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.942
pfkA
6-phosphofructokinase isozyme 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.938
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.935
glpX
Fructose-1,6-bisphosphatase 1 class 2.
    
 0.928
lacC_1
Tagatose-6-phosphate kinase.
     
 0.907
lacC_2
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.907
lacC_3
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.907
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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