STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcaR_2Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. (298 aa)    
Predicted Functional Partners:
benM_2
HTH-type transcriptional regulator BenM.
  
     0.719
oxyR_1
Hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family.
  
     0.718
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
    0.713
tfdS
HTH-type transcriptional regulator TfdS; Belongs to the LysR transcriptional regulatory family.
  
     0.593
hcaR_1
Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family.
  
     0.512
allS_2
HTH-type transcriptional activator AllS; Belongs to the LysR transcriptional regulatory family.
  
     0.447
gcvA_3
Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family.
  
     0.424
dmlR_6
HTH-type transcriptional regulator DmlR.
  
     0.417
catM
HTH-type transcriptional regulator CatM; Belongs to the LysR transcriptional regulatory family.
  
     0.412
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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