Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfaCLipopolysaccharide heptosyltransferase 1. (320 aa)    
Predicted Functional Partners:
rfaF
ADP-heptose--LPS heptosyltransferase 2.
 
0.998
rfaQ
Lipopolysaccharide core heptosyltransferase RfaQ.
 
  
 0.981
rfaG
Lipopolysaccharide core biosynthesis protein RfaG.
 
 
 0.975
waaA
3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
 0.966
rfaP
Lipopolysaccharide core heptose(I) kinase RfaP.
 
 
 0.964
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.950
rfaY
Lipopolysaccharide core heptose(II) kinase RfaY.
   
 
 0.930
gspA_3
General stress protein A.
 
 
 0.927
gspA_2
General stress protein A.
 
 
 0.925
APC14051.1
O-Antigen ligase.
  
 
 0.914
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
Server load: low (16%) [HD]