STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4N511_THEPAMediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (346 aa)    
Predicted Functional Partners:
Q4MZF4_THEPA
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.999
Q4N6V0_THEPA
Ubiquitin/ribosomal fusion protein, putative.
    
 0.881
MT-CYB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
   
 
 0.865
Q4N1I7_THEPA
Ribosomal_S27 domain-containing protein.
    
 0.838
Q4N648_THEPA
60S ribosomal protein L21e, putative.
   
 
 0.833
Q4N6W9_THEPA
60S ribosomal protein L8, putative.
   
 
 0.813
Q4N2G2_THEPA
60S ribosomal protein L13, putative.
   
 
 0.812
Q4N4T6_THEPA
Sulfate transporter, putative.
    
 
 0.808
Q4N5U0_THEPA
Proteasome regulatory subunit, putative.
    
 0.797
Q4N5K7_THEPA
60S ribosomal protein L39, putative.
   
   0.777
Your Current Organism:
Theileria parva
NCBI taxonomy Id: 5875
Other names: T. parva
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