STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (477 aa)    
Predicted Functional Partners:
SES38482.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.973
SES40575.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.946
SES47593.1
Cystathionine beta-synthase.
 
 0.883
SER68648.1
Cystathionine gamma-synthase.
  
 0.881
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.880
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.878
SES35869.1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.874
SES48742.1
O-acetylhomoserine sulfhydrylase.
     
 0.870
SES08332.1
Cobalamin-independent synthase, Catalytic domain.
  
 
 0.861
SER72165.1
Homoserine dehydrogenase.
   
 
  0.854
Your Current Organism:
Phycicoccus cremeus
NCBI taxonomy Id: 587636
Other names: CGMCC 1.6963, JCM 17739, NBRC 104261, P. cremeus, Phycicoccus cremeus Zhang et al. 2011, Phycicoccus sp. V2M29, strain V2M29
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